4-Bromo-2,6-difluorophenylboronic acid(Contains varying amounts of anhydride)
(4-Bromo-2,6-difluorophenyl)boronic acid
CAS: 352535-81-0
Molecular Formula: C6H4BBrF2O2
4-Bromo-2,6-difluorophenylboronic acid(Contains varying amounts of anhydride) - Names and Identifiers
4-Bromo-2,6-difluorophenylboronic acid(Contains varying amounts of anhydride) - Physico-chemical Properties
| Molecular Formula | C6H4BBrF2O2 |
| Molar Mass | 236.81 |
| Density | 1.82±0.1 g/cm3(Predicted) |
| Melting Point | 155-160°C(lit.) |
| Boling Point | 298.4±50.0 °C(Predicted) |
| Flash Point | 134.3°C |
| Vapor Presure | 0.000569mmHg at 25°C |
| Appearance | Solid |
| pKa | 7.91±0.58(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.547 |
| MDL | MFCD03095369 |
4-Bromo-2,6-difluorophenylboronic acid(Contains varying amounts of anhydride) - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| WGK Germany | 3 |
| Hazard Note | Irritant |
4-Bromo-2,6-difluorophenylboronic acid(Contains varying amounts of anhydride) - Introduction
(4-Bromo-2,6-difluorophenyl)boronic acid is an organic compound with the chemical formula C6H4BrBF2O2. It is a white crystalline solid, relatively stable at room temperature.
Regarding its properties, first of all, it has high thermal stability and can be heated at a higher temperature without decomposition. Secondly, it can be dissolved in some organic solvents, such as dimethyl sulfoxide (DMSO), acetonitrile and chloroform. In addition, it is also a weak acid that can react with bases to form the corresponding salts.
(4-Bromo-2,6-difluorophenyl)boronic acid has a wide range of applications in chemical research and synthesis. It is an important organoboron reagent, which can be used in the synthesis of borohydrides, the formation of C- C bonds and the functionalization of electron-rich groups. In addition, it can also be used as a building block for fluorescent dye molecules.
The preparation of (4-Bromo-2,6-difluorophenyl)boronic acid can be carried out in a variety of ways. One of the common methods is the reaction of 4-bromo-2, 6-difluorobenzene with trimethylborane in a reaction solvent, and the product is obtained by a ligand exchange reaction.
Regarding safety information, 4-bromo-2, 6-difluorophenylboronic acid needs to be stored dry, low temperature, and away from oxidizing agents, acids, etc. In the operation, need to wear appropriate protective measures, such as gloves and goggles, to avoid contact with it may cause harm to the human body. At the same time, avoid inhaling its dust or solution, avoid contact with skin and eyes. In case of contact, flush with plenty of water and seek medical help.
Regarding its properties, first of all, it has high thermal stability and can be heated at a higher temperature without decomposition. Secondly, it can be dissolved in some organic solvents, such as dimethyl sulfoxide (DMSO), acetonitrile and chloroform. In addition, it is also a weak acid that can react with bases to form the corresponding salts.
(4-Bromo-2,6-difluorophenyl)boronic acid has a wide range of applications in chemical research and synthesis. It is an important organoboron reagent, which can be used in the synthesis of borohydrides, the formation of C- C bonds and the functionalization of electron-rich groups. In addition, it can also be used as a building block for fluorescent dye molecules.
The preparation of (4-Bromo-2,6-difluorophenyl)boronic acid can be carried out in a variety of ways. One of the common methods is the reaction of 4-bromo-2, 6-difluorobenzene with trimethylborane in a reaction solvent, and the product is obtained by a ligand exchange reaction.
Regarding safety information, 4-bromo-2, 6-difluorophenylboronic acid needs to be stored dry, low temperature, and away from oxidizing agents, acids, etc. In the operation, need to wear appropriate protective measures, such as gloves and goggles, to avoid contact with it may cause harm to the human body. At the same time, avoid inhaling its dust or solution, avoid contact with skin and eyes. In case of contact, flush with plenty of water and seek medical help.
Last Update：2024-04-10 22:29:15
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Product Name: 4-Bromo-2,6-difluorophenylboronic acid(Contains varying amounts of anhydride) Visit Supplier Webpage Request for quotationCAS: 352535-81-0
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View History
4-Bromo-2,6-difluorophenylboronic acid(Contains varying amounts of anhydride)
N-(1-Oxododecyl)-L-glutamic acid, bis(2-octyldodecyl) ester
Paliperidone Impurity 30
alpha-Amino-omega-carboxy poly(ethylene glycol) hydrochloride (PEG-MW 5.000 Dalton)
[4-[(4-chlorophenyl)cyanomethyl]-5-chloro-m-tolyl]ammonium chloride
ETHYLENEDIAMINETETRAACETIC ACID DICALCIUM SALT
N'-{2-[(2-chlorobenzyl)oxy]-3-methoxybenzylidene}benzohydrazide
RARECHEM AL BW 0300
N-(1-Oxododecyl)-L-glutamic acid, bis(2-octyldodecyl) ester
Paliperidone Impurity 30
alpha-Amino-omega-carboxy poly(ethylene glycol) hydrochloride (PEG-MW 5.000 Dalton)
[4-[(4-chlorophenyl)cyanomethyl]-5-chloro-m-tolyl]ammonium chloride
ETHYLENEDIAMINETETRAACETIC ACID DICALCIUM SALT
N'-{2-[(2-chlorobenzyl)oxy]-3-methoxybenzylidene}benzohydrazide
RARECHEM AL BW 0300